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Research has uncovered a natural, healthful chemical compound found in flaxseed that has shown to have promising results on cancer prevention. This chemical compound is lignan. Lignans are classified as phytoestrogens and have both weak oestrogenic and anti oestrogenic actions.
Common Flaxis one of the luxuriantest sources of vegetable lignans; it is made with 70 800 times more lignans compared with any other plant. The major lignan in flaxseed is secoisolariciresinol diglycoside Sdg. Following ingestion, vegetable based lignans are converted in the large intestine into two mammalian lignans: Enterolactone and enterodiol. The two chemical compounds are absorbed from the intestine and undergo enterohepatic circulation.
A elevated consumption of dietary vegetable lignans is associated with elevated levels of mammalian lignans in blood serum and urine. Therefore, lignans may act as early biomarkers for the incidence of certain disease states.
Lignans were once widespread in the diet; the Western diet has eliminated much of the unrefined grains and opted for process foods. With a strong body of evidence that suggests lignans elevate breast health, the addition of flaxseed or a lignan supplement to your diet is a must to women's health.
Breast Cancer is one of the most prevalent diseases in women. One in 11 Australian women will be diagnosed with breast cancer before they turn 75. More compared with 11,000 women are diagnosed with breast cancer each year in Australia. The disease kills about 400,000 women globally each year. Figures demonstrate that 85 Percent of women aged 40 69 are alive, five years after diagnosis and the survival rate is much lower for younger women.
About Oestrogen
Oestrogen is critical to women's physical development and functions. Every cell in the body has oestrogen receptors and oestrogen nourishment is essential for the body to function normally. Because women are exposed to varying levels of estrogen during the entire adulthood, maintaining a hormonal balance to enable a healthful lifetype is a complex challenge.
Oestrogen levels are typically elevated in women during the childbearing years and then fall away through the perimenopausal and postmenopausal years. With inadequate oestrogen a woman can experience symptoms like hot flushes, mood modifications and a loss of bone density. On the other hand, with too much oestrogen, symptoms can range from Pms to more critical events like unhealthful breast tissue.
Breast cells contain specific oestrogen receptors which are tailored like a lock and only the right shaped key will fit the lock. In this case, the key is free oestrogen. Normally, the body's free oestrogen in the blood attaches to a breast cell and completely naturally occurring enzymes cause the breast cell to grow and divide in an orderly manner so that worn out or injured tissue is replaced or repaired. The more oestrogen that is available, the more rapid the growth and division of breast cells. If cells duplicate or grow in an abnormal way a mass lump may develop.
Phytoestrogens. Plant Lignans
Management of oestrogen levels with vegetable phytoestrogens was a topic of research for a number of years. Isoflavonoids and lignans are two commonly occurring phytoestrogens. Isoflavonoids occur principally in soya while lignans occur in most plants. The luxuriantest source is in flaxseed Linum usitatissimum also acknowledged as Linseed, with 70 800 times more lignans compared with any other plant. Flaxseed was established to have numerous protective effects in epidemiological, animal and cell analyses of breast tissue.
The major lignan in flaxseed is secoisolariciresinol Sdg. When Sdg is ingested, it is transformed onto mammalian lignans Enterodiol and Enterolactone by gut bacteria. Mammalian lignans are believed not only to have chemo protective attributes, but to be potent anti oxidants.
Every woman concerned with vitality, and, health longevity should consider taking Lignan Life. It represents a recent paradigm of proactive breast health that is dedicated to addressing breast health before a problem occurs.
Proactive breast health is firmly founded on the model of the oestrogen window, and the really real possibility of managing one's own oestrogen window toward the attainment of optimal breast health.
When utilising Lignan Life you may not feel any noticeable change in your body. For many women, the satisfaction in knowing that they are taking a proactive step toward optimal breast health is sufficiently motivation. However, women have also reported a range of potential side advantages, and you might experience the after when taking Lignan Life on a regular basis.
Women have reported a reduction in menopause and Pms related symptoms, like reduction in
hot flashes
bloating
breast tenderness.
Some women may experience a slight lengthening of their menstrual cycle. For example, that might mean they experience a 30 day cycle rather compared with a 28 day cycle. While this may not appear to be a benefit at all, you may experience fewer periods during your remerchandiseive years, and decrease your lifetime exposure to oestrogen as a result.
There are no acknowledged adverse effects related to lignan supplementation. As with all nutritional supplements or pharmaceutical drugs, suggested doses of Lignan Life should not be exceeded without the advice of a licenced health care professional.
Lignan Life is comprised of a really special and specific vegetable lignan which was standardized, condensed, purifiedisolated, and, guaranteed for strength from flaxseed. Flaxseed is the most highly researched source of vegetable lignans.
While flaxseed is the world's most abundant source of lignans, the concentration of lignan from crop to crop, for that matter, variety to variety and from seed to seed, can fluctuate up to 300 Percent Lignan Life guarantees to transport an exact dose every time, tailored to raise the body's physiologic concentration of lignans to that of women on a really conscientious, vegetarian diet and with an excellent history of breast health.
The effect of Lignan Life is almost immediate. Within one week of taking Lignan Life, lignan levels equal or slightly exceed those in women who have established an elevated extent of breast health.
Once you stop taking Lignan Life, supplemental lignan levels and their proactive effects are gone within 48 to 72 hours.
Supplemental lignan levels are quickly reestablished once Lignan Life supplementation is reinstated.
Pregnant women or breastfeeding mothers should not take Lignan Life.
With the exception of early gestation, women are exposed to lower compared with average levels of estrogen while pregnant and lactating. The body effectively closes the oestrogen window during this time, temporarily negating the need for Lignan Life.
Further, though no negative fallouts have been reported in relation to women, lignans, and lactation, ,gestation Lignan Life has not been tested in pregnant or lactating women. If you are taking Lignan Life and discover after the fact that you are pregnant, simply discontinue use until after the birth of your child and after lactation/breastfeeding has ceased.
Women undergoing breast, ovarian or cervical cancer treatments should consult with their physician before taking any nutritional supplement including Lignan Life.
Lignan Life is comprised of natural, healthful vegetable lignans and is therefore not a pharmaceutical drug. Natural merchandises cannot legally be sold to treat or prevent illness, only to support the structure or function of the body. However, a physician has the right to use any means within his or her power to treat or prevent disease Ð including nutritional supplements. Lignans, isolated, condensed, purified and standardized for strength in Lignan Life, have been shown to support the structure and function of the body to assure healthful breast tissue.
Maintaining a healthful diet and lifetype are crucial factors to assure a healthful future. For some pharmaceuticals like Tamoxifen® the effectualness of the drug wanes and should be discontinued after five years. For women interested in the preservation of healthful breast tissue long term, they may wish to consult with their physician to see If Lignan Life is a good choice for them. As with all pharmaceuticals or nutritional supplements, you should consult with your physician before use after or during the treatment of a serious illness.
The majority of breast cancers are not hereditary. In fact, only 10 Percent of breast cancers can be owed to a hereditary predisposition. The remaining 90 Percent of breast cancers are owed to lifetype, environmental, dietary and unknown causes.
Product Sizes
Lignan Life is made with 60 tablets each with 50 mg of Sdg.
Flaxseed Lignan Research
Encouraged by results in animal models, Thompson et al conducted a randomized double blind placebo controlled trial to determine the effect of flaxseed on 39 women with newly diagnosed breast cancer. Patients received 25 grams of flaxseed, or a placebo, daily for an average of 39 days before surgery. The patients who received the flaxseed had reduced tumor cell proliferation at a rate similar to the effects shown with Tamoxifen®.
Many epidemiological analyses have discovered that women with an elevated urinary excretion of lignans have lower risk of developing unhealthful breast tissue compared with women who excrete low amounts of lignans.
The protective effects of flaxseed lignans on breast tissue may be due to several mechanisms including the ability to interfere with oestrogen the metabolic rate. Experiments over the past 20 years have shown that a large part of the cancer inducing effect of oestrogen involves the formation of antagonistic metabolites of oestrogen, particularly 16 alpha hydroxyestrone. Other metabolites, like 2 hydroxyestrone offer defense.12 Analyses in both peri and postmenopausal women have shown that daily consumption of ground flaxseed elevated 2 hydroxyestrone.
Mammalian lignans have a similar structure to oestrogen which means that they can fit the same lock on the breast cells and block the entry of free oestrogen. It's thought that the mammalian lignans increase the completely naturally occurring enzyme that directs the break down of free oestrogen to the 2 hydroxyestrone.
In addition, observation and in vitro analyses suggest lignans may stimulate the synthesis of sex hormone binding globulin Shbg, a protein that binds more compared with 95 Percent of steroid sex hormones circulating in the body. An increase in Shbg would give rise to lower free oestrogen concentrations, bestowing a chemo protective effect.
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